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Korean J Pediatr 1995 September;38(9) :1220-1231.
Results of the Mechanical Valve Replacement in the Right Side of the Heart in Children
Hyeon Jin Park (Park HJ), Chung Il Noh (Noh CI), Ho Sung Kim (Kim HS), Jung Yun Choi (Choi JY), Yong Soo Yun (Yun YS), Yong Jin Kim (Kim YJ)
Department of Pediatrics and Thoracic Surgery, Seoul National University, College of Medicine, Seoul, Korea
Copyright © 1995 by The Korean Pediatric Society
Purpose : We performed this study in order to evaluate the outcome of the mechanical valve replacement in the right side of the heart in children. Methods : Retrospective analysis of the clinical records of 26 patients who had undergone a right sided valve replacement between October 1986 and September 1992 at Seoul National University Children뭩 Hospital. Results : Twenty six children underwent 27 mechanical valve replacement (tricuspid in 7; pulmonary in 20). Overall, 17(63.0%) out of 27 developed valve dysfunction. It occurred in 6(85.7%) of 7 in the tricuspid position, 26.17+24.51 months after replacement and in 11(55.0%) of 20 in the pulmonary position, 11.64+9.28 months after replacement. The main presenting symptoms were dyspnea in 5 (3 tricuspid, 2 pulmonary), facial edema in 1; the others were asymptomatic. Concurrent auscultatory findings were: disappeared valve click in 16, new diastolic murmur in 7, and increased systolic ejection murmur in 1. In all cases, low level of anticoagulation (INR < 2.0) was maintained by coumadin, with or without antiplatelet drugs. Among valve dysfunction cases, thrombloytic therapy with urokinase was attempted in 5 and reoperation in 7. Of 5 thrombolytic trial, treatment was successful in 3 and failed in 1. One died of severe right heart failure 4 hours after urokinase infusion. Operative procedure were valve replacement in 6 (another mechanical valve in 2, tissue valve in 4) and right ventricular outflow tract widening without valve insertion in 1. During the following up without specific treatment in remaining cases, all were asymptomatic. Valve click restored spontaneously in 3 cases 5 to 17 months after disappearance of click. Conclusion : The replacement with mechanical valve in the right side of the heart in children is associated with high incidence of dysfunction and should be avoided as possible as can be. Although thrombolytic therapy is effective in the treatment of mechanical valve thrombosis, close monitoring is needed to avoid complications. It is uncertain that asymptomatic valve dysfunction in the pulmonary position should always be treated to restore normal valve function.
Keywords: Mechanical valve dysfunction | Tricuspid | Pulmonary | Thrombolytic therapy
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Supplementary Material  Supplementary Material
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