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Korean J Pediatr 1995 September;38(9) :1270-1275.
Three Cases of Rotor Syndrome in Monozygotic Twin Brothers and Their Sister
Jin Hwa Jung (Jung JH), Jeong Ho Lee (Lee JH), Yong Sub Kim (Kim YS), Jong Dae Jo (Jo JD)
Department of Pediatrics, Maryknoll Hospital, Busan, Korea
Copyright © 1995 by The Korean Pediatric Society
We recently experienced three cases of Rotor syndrome in monozygotic twin brothers and their elder sister. The only clinical manifestation was persisting mild jaundice for several years. In all three cases serum bilirubin, mainly of direct reacting was increased with normal liver function and normal hepatic histology without pigmentation by needle liver biopsy. Indocyanine green test showed marked serum retention after 15 minutes and cholescintigraphy showed that liver was seen very faintly and persistent visualization of the cardiac pool and prominent kidney excretion after 60 minutes. A brief reviews of related literature was made.
Keywords: Rotor syndrome
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