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Korean J Pediatr 2000 August;43(8) :1149-1152.
A Case of Fixed Drug Eruption Due to Acetaminophen
Eui Jeong Min (Min EJ)1, Dae Hyun Lim (Lim DH)1, Jung Hee Kim (Kim JH)1, Seung Won Choi (Choi SW)2, Byong Kwan Son (Son BK)3
1Department of Pediatrics, College of Medicine, Inha University, Korea
2Department of Internal Medicine, College of Medicine, Inha University, Korea
3Department of Pediatrics, College of Medicine, Inha University, Korea
Copyright © 2000 by The Korean Pediatric Society
Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often leaves residual hyperpigmentation. Commonly implicated substances are phenolphthalein, barbiturates, sulfonamides, tetracyclines, salicylates, gold and pyrazolone derivatives. Despite frequent use of acetaminophen, drug eruptions, especially fixed drug eruptions, due to acetaminophen are extremely rare. We report here a childhood case of fixed drug eruption caused by acetaminophen, which is extensively used as an over-the-counter drug, as well as in medical therapy.
Keywords: Acetaminophen | Fixed drug eruption
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