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CASE REPORT
Korean J Pediatr 2005 August;48(8) :901-906.
Giant Coronary and Axillary Aneurysms in an Infant with Kawasaki Disease Associated with Thrombocytopenia
Sei Young Seo (Seo SY), Jin Hee Oh (Oh JH), Jong-Hyun Kim (Kim JH), Ji-Whan Han (Han JW), Kyung-Yil Lee (Lee KY), Dae Kyun Koh (Koh DK)
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
Corresponding Author: Jin Hee Oh ,Email: Jeany@catholic.ac.kr
Copyright © 2005 by The Korean Pediatric Society
ABSTRACT
Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Yet the etiology of KD is still unknown and diagnosis depends on the exclusion of other diseases and the clinical manifestations meeting the defined criteria. Young infants frequently show atypical clinical courses and are frequently complicated with coronary aneurysms. Some cases show thrombocytopenia, which is known as one of the risk factors for complications with coronary aneurysms. So, a high index of suspicion is the most important factor for the diagnosis of KD in very young infants or adolescents whose clinical courses are equivocal. We report herein on a case of KD in an 80-day-old female infant with fever and seizure with bloody stool; laboratory findings were those of sepsis with disseminated intravascular coagulopathy. In spite of aggressive treatments, fever and thrombocytopenia persisted for two weeks and huge coronary aneurysms developed at the third week in all three major coronary arteries; the diameter of the right one was as large as the aortic annulus. Three months later, huge pulsatile masses developed in both axillas; these were found to be huge axillary aneurysms defined very clearly on multi-detector CT scan. She has been under follow up with antiplatelets and anticoagulation therapy with poor regression of the aneurysms.
Keywords: Mucocutaneous lymph node syndrome | Infant | Thrombocytopenia | Coronary aneurysm | Axillary aneurysm
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Thrombolytic Therapy and Long Term Follow-up Study in a Child with Kawasaki Disease Complicated by Giant Coronary Aneurysm with Thrombosis  2003 March;46(3)
3 Cases of Kawasaki Disease Associated Thrombocytopenia  1995 December;38(12)
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