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ORIGINAL ARTICLE
Korean J Pediatr 2005 October;48(10) :1139-1142.
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park (Park YW)1, Ji Whan Han (Han JW)2, In Sook Park (Park IS)3, Chang Hwi Kim (Kim CH)4, Sung Ho Cha (Cha SH)5, Jae Sook Ma (Ma JS)6, Tae Chan Kwon (Kwon TC)7, Sang Bum Lee (Lee SB)8, Chul Ho Kim (Kim CH)1, Heung Jae Lee (Lee HJ)9, Yong Soo Yun (Yun YS)10
1Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea
2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea
3Department of Pediatrics, College of Medicine, University of Ulsan, Korea
4Department of Pediatrics, College of Medicine, Soonchunhyang University, Buchun, Korea
5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
6Department of Pediatrics, College of Medicine, Chonnam National University, Kwangju, Korea
7Department of Pediatrics, College of Medicine, Keimyung University, Daegu, Korea
8Department of Pediatrics, College of Medicine, Kyungpook National University, Daegu, Korea
9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea
10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
Corresponding Author: Yong Won Park ,Email: yongpw@hanmail.net
Copyright © 2005 by The Korean Pediatric Society
ABSTRACT
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. Results : 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. Conclusion : Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%).
Keywords: Kawasaki disease | Mucocutaneous lymph node syndrome | Coronary aneurysm | Epidemiology | Child
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