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ORIGINAL ARTICLE
Korean J Pediatr 2008 December;51(12) :1320-1323.
doi:https://doi.org/10.3345/kjp.2008.51.12.1320
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park (Park YW)1, Ji Whan Han (Han JW)2, In Sook Park (Park IS)3, Chang Hwi Kim (Kim CH)4, Sung Ho Cha (Cha SH)5, Jae Sook Ma (Ma JS)6, Joon Sung Lee (Lee JS)2, Tae Chan Kwon (Kwon TC)7, Sang Bum Lee (Lee SB)8, Chul Ho Kim (Kim CH)1, Heung Jae Lee (Lee HJ)9, Yong Soo Yun (Yun YS)10
1Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea
2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea
3Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea
4Department of Pediatrics, College of Medicine, Soonchunhyang University, Korea
5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
6Department of Pediatrics, College of Medicin, Chonnam National University, Kwangju, Korea
7Department of Pediatrics, College of Medicine, Keimyung University, Taegu, Korea
8Department of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea
9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea
10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
Corresponding Author: Yong Won Park ,Email: yongpw@hanmail.net
Copyright © 2008 by The Korean Pediatric Society
ABSTRACT
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants 6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients 6 months of age were analyzed and compared with those of KD patients >6 months of age. Results : A total of 1,739 patients 6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67:1. Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively. Conclusion : Comparison of data from KD patients >6 months old with data from 1,739 KD patients 6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients.
Keywords: Mucocutaneous lymph node syndrome | Coronary aneurysm | Epidemiology | Infant
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