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Korean J Pediatr 2017 March;60(3) :64-69.
Published online 2017 March 15.       
Postdischarge growth assessment in very low birth weight infants
Joon-Sik Park, Jungho Han, Jeong Eun Shin, Soon Min Lee, Ho Seon Eun, Min-Soo Park, Kook-In Park, Ran Namgung
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
Corresponding Author: Soon Min Lee ,Tel: +82-2-2019-3350, Fax: +82-2-3461-9473, Email:
Copyright © 2017 by The Korean Pediatric Society
Purpose: The goal of nutritional support for very-low-birth-weight (VLBW) infants from birth to term is to match the in utero growth rates; however, this is rarely achieved.
Methods: We evaluated postdischarge growth patterns and growth failure in 81 Korean VLBW infants through a retrospective study. Weight and height were measured and calculated based on age percentile distribution every 3 months until age 24 months. Growth failure was defined as weight and height below the 10th percentile at 24 months. For the subgroup analysis, small-for-gestational age (SGA) and extremely low birth weight (ELBW) infants were evaluated. The growth patterns based on the Korean, World Health Organization (WHO), or Centers for Disease Control and Prevention (CDC) standard were serially compared over time.
Results: At postconception age (PCA) 40 weeks, 47 (58%) and 45 infants (55%) showed growth failure in terms of weight and height, respectively. At PCA 24 months, 20 infants (24%) showed growth failure for weight and 14 (18%) for height. Growth failure rates were higher for the SGA infants than for the appropriate-weight-for-gestational age infants at PCA 24 months (P=0.045 for weight and P=0.038 for height). Growth failure rates were higher for the ELBW infants than for the non-ELBW infants at PCA 24 months (P<0.001 for weight and P=0.003 for height). Significant differences were found among the WHO, CDC, and Korean standards (P<0.001).
Conclusion: Advancements in neonatal care have improved the catch-up growth of VLBW infants, but this is insufficient. Careful observation and aggressive interventions, especially in SGA and ELBW infants, are needed.
Keywords: Very low birth weight infant | Small for gestational age infant | Gestational age | Extremely low birth weight infant | Premature infant
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Modification of nutrition strategy for improvement of postnatal growth in very low birth weight infants  2016 April;59(4)
Nutritional strategy of early amino acid administration in very low birth weight infants  2015 March;58(3)
Thyroid dysfunction in very low birth weight preterm infants  2015 June;58(6)
Idiopathic severe hypermagnesemia in an extremely low birth weight infant on the first day of life  2011 July;54(7)
Testicular torsion in the inguinal region in an extremely low birth weight infant  2010 September;53(9)
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