Advanced Search
Korean J Pediatr 2018 April;61(4) :108-113.
Published online 2018 April 15.       
Sudden unexpected cardio-respiratory arrest after venipuncture in children
Goun Jeong1, Son Moon Shin1, Nam Su Kim2, Young Min Ahn3
1Department of Pediatrics, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea
2Department of Pediatrics, Hanyang University College of Medicine, Seoul, Korea
3Department of Pediatrics, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea
Corresponding Author: Young Min Ahn ,Tel: +82-2-970-8228, Fax: +82-2-976-5441, Email:
Copyright © 2018 by The Korean Pediatric Society
Purpose: This study aimed to investigate the clinical and socioenvironmental characteristics of sudden cardiorespiratory arrest after venipuncture in children.
Methods: We conducted a retrospective email-based survey of all members of the Korean Pediatric Society. The questionnaire included items on patient demographics, socioenvironmental circumstances of the venipuncture, type of cardiorespiratory arrest, symptoms and signs, treatment, prognosis, and presumed cause of the arrest.
Results: Fourteen patients were identified. Of these, 13 were young children (<2 years old), and 1 was 14 years old. All patients had been previously healthy and had no specific risk factors for sudden cardiorespiratory arrest. Most cases (n=11, 79%) were defined as cardiac or cardiorespiratory arrest, while the remaining cases (n=3, 21%) were defined as respiratory arrest. Aspiration (n=3), acute myocarditis (n=2), and laryngeal chemoreflex (n=1) were presumed as the causes; however, the exact causes were unclear. The overall prognosis was poor (death, n=7; morbidity, n=5; full recovery, n=2). The medical institutions faced severe backlash because of these incidents (out-of-court settlement, n=5; medical lawsuit, n=5; continuous harassment, n=3).
Conclusion: Cardiorespiratory arrest after venipuncture is unpredictable and the probable cause of most cases is a vasovagal reaction. Medical personnel must be aware of the risk of unexpected cardiorespiratory arrest during routine intravenous procedures.
Keywords: Venipuncture | Heart arrest | Vasovagal reaction | Child | Cardiopulmonary resuscitation
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Supplementary Material  Supplementary Material
Acute viral lower respiratory tract infections in children  2009 March;52(3)
A study for headaches and backaches occurrence after diagnostic lumbar puncture in children  2006 July;49(7)
A Clinical Study of the Acute Respiratory Distress Syndrome in Children  2003 January;46(1)
Survey on Upper Respiratory Tract Infections in Children  2001 June;44(6)
A Clinical Study on Acute Lower Respiratory Tract Infections by Adenovirus in Children  1998 August;41(8)
Register for e-submission
Register here to access the e-submission system of Korean J Pediatr for authors and reviewers.
Manuscript Submission
To submit a manuscript, please visit the Korean J Pediatr e-submission management system at, read the Instructions for Authors, and log into the Korean J Pediatr e-submission system. For assistance with manuscript submission, please contact:
Free archive
Anyone may access any past or current articles without logging in.
Korean Pediatric Society Office
#1606, Seocho World Officetel, 19 Seoun-ro, Seocho-gu, Seoul 137-070, Korea
TEL : +82-2-3473-7305    FAX : +82-2-3473-7307   E-mail:
BrowseCurrent IssueFor Authors and ReviewersAbout
Copyright© The Korean Pediatric Society. All right reserved.