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REVIEW ARTICLE
Korean J Pediatr 2013 October;56(10) :431-438.
Published online 2013 June 04.       
Magnetoencephalography in pediatric epilepsy
Hunmin Kim1, Chun Kee Chung2,3, Hee Hwang1,4
1,4Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
1Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea
2,3Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
Magnetoencephalography Center, Seoul National University Hospital, Seoul, Korea
Corresponding Author: Hee Hwang ,Tel: 031-787-7284, Fax: 031-787-4054, Email: neuroandy@snubh.org
Copyright © 2013 by The Korean Pediatric Society
ABSTRACT
Magnetoencephalography (MEG) records the magnetic field generated by electrical activity of cortical neurons. The signal is not distorted or attenuated, and it is contactless recording that can be performed comfortably even for longer than an hour. It has excellent and decent temporal resolution, especially when it is combined with the patients own brain magnetic resonance imaging (magnetic source imaging). Data of MEG and electroencephalography are not mutually exclusive and it is recorded simultaneously and interpreted together. MEG has been shown to be useful in detecting the irritative zone in both lesional and nonlesional epilepsy surgery. It has provided valuable and additive information regarding the lesion that should be resected in epilepsy surgery. Better outcomes in epilepsy surgery were related to the localization of the irritative zone with MEG. The value of MEG in epilepsy surgery is recruiting more patients to epilepsy surgery and providing critical information for surgical planning. MEG cortical mapping is helpful in younger pediatric patients, especially when the epileptogenic zone is close to the eloquent cortex. MEG is also used in both basic and clinical research of epilepsy other than surgery. MEG is a valuable diagnostic modality for diagnosis and treatment, as well as research in epilepsy.
Keywords: Magnetoencephalography | Epilepsy | Pediatric
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