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Journal of the Korean Pediatric Society 1993;36(10):1458-1465.
Published online October 15, 1993.
Two Cases of Virus Associated Hemophagocytic Syndrome
Jae Hee Han1, Hyun Chul Lee1, Hwang Min Kim1, Jong Soo Kim1, Kyung Won Lee2
1Department of Pediatrics, Wonju College of Medicine, Yonsei University, Wonju, Korea, Department of Radiology
2Department of Clinical Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea, Department of Radiology
Virus Associated Hemophagocytic Syndrome 2례
한재희1, 이현철1, 김황민1, 김종수1, 이경원2
1연세대학교 원주의과대학 소아과학교실
2연세대학교 원주의과대학 임상병리학교실
Abstract
Virus associated hemophagocytic syndrome, class II histiocytoses, characterized by high fever, severe constitutional symptoms, abnormal liver function and coagulation, peripheral blood pancytopenia and histiocytic hyperplasis with prominent hemophagocytosis in bone marrow and lymph nodes has been reported and associated with active viral infection. It is non-malignant and reversible. It must be differentiated from histiocytic medullary reticuosis because of the inappropriateness of immunosuppressive or cytotoxic therapy which is the therapeutic method for HMR, but is contraindicated in the treatment of VAHS. This paper describes two patients whose clinicopathology was compatible with the diagnosis of virus associated hemophagocytic syndrome.
Key Words: Virus associated hemophagocytic syndrome


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