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Journal of the Korean Pediatric Society 1995;38(10):1422-1428.
A Case of Cutaneous Polyarteritis Nodosa
Hyun Chul Chae, Kyung Hee Choi, Mi Soo Ahn, Ji Sub Oh
Department of Pediatrics, Wallace Memorial Baptist, Hospital, Busan, Korea
피부형 결절성 다발동맥염 1례
채현철, 최경희, 안미수, 오지섭
왈레스기념칠례회 소아과
Polyarteritis nodosa(PAN), one of the necrotizing vasculitis involving predominantly small and medium sized arteries, is rare disease. PAN may affect many organs such as kidney, heart, liver, gastrointestinal tract, muscles and skin. Cutaneous PAN, a distinct clinical entity, is chronic and benign vascular disease in which cutaneous lesions are predominant with no visceral involvement. We experienced a case of cutaneous PAN in a 7-year old boy, which was diagnosed by clinical finding and biopsies of subcutaneous nodules. He had cutaneous or subcutaneous nodules which caused localized tenderness, and livedo reticularis. Histopathological examination of the nodular lesions showed panarteritis of small and medium sized arteries with diffuse round cell infiltration. There seems to be an association between prior group A streptococcal infection and childhood PAN. Laboratory study of our patient showed an elevated ASLO titer. Corticosteroid has improved the prognosis and combined use of corticosteroid and immunosuppressive drugs may be even better for some patients. He was treated with oral prednisolone and showed a good clinical response.
Key Words: Polyarteritis nodosa, Childhood, Cutaneous form


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