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Journal of the Korean Pediatric Society 2002;45(7):912-916.
Published online July 15, 2002.
A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor
Byoung Chul Kwon1, Kyung Mi Shin1, Sung Chul Won1, Chuhl Joo Lyu1, Chang Hyun Yang1, Hyun Ok Kim2
1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea
2Department of Clinical Pathology, College of Medicine, Yonsei University, Seoul, Korea
급성 골수구성 백혈병 환아에서 비혈연간 주조직 적합항원 3부위 불일치 제대혈 조혈모세포 이식 성공 1례
권병철1, 신경미1, 원성철1, 유철주1, 양창현1, 김현옥2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 임상병리학교실
Correspondence:  Chuhl Joo Lyu,
Email: cj@yumc.yonsei.ac.kr
Abstract
Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and the platelet recovered greater than 20,000/mm3 independent of transfusion at day 81 after stem cell infusion.
Key Words: Cord blood transplantation, HLA-3 loci mismatching, Unrelated donor
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